Figure 1.
Constitutive activation of NF-κB in lysMCreIκBαfl/fl monocytes. Representative cytospins of naïve CD11b-sorted spleen monocytes from lysMCreIκBαfl/fl mice (A) or wild-type controls (B) after staining for the NF-κB p65 subunit and nuclear co-staining with TOTO-3. Note the accumulation of active NF-κB in the nucleus of monocytes from a representative lysMCreIκBαfl/fl mouse (marked by arrows). Bar = 20 μm.