Table 5.

Results of the multivariate analysis

Parameter	p value	Hazard ratio	95% confidence interval for Hazard ratio
No. of metastases > 1 vs. 1	0.041	1.77	1.02-3.05
Total target volume (cc) ≤ 6 vs. > 6	0.049	0.59	0.35-0.99
Extracranial disease progressive vs. absent or controlled	0.005	2.55	1.33-4.87
IT (months) ≥ 60 vs. < 60	0.024	0.34	0.14-0.87
KPS score ≠70 vs. = 70	0.140	0.66	0.39-1.14
Histologic characteristics Melanoma vs. Others	0.416	1.66	0.49-5.58

IT, interval time; KPS, Karnofsky performance score