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. 2012 Feb 7;10(2):e1001258. doi: 10.1371/journal.pbio.1001258

Table 1. Regions under selection in the sheep genome.

Region Chr Position (Mb) Peak SNP (F ST) Top SNP Genes Candidates
1 2 55.25–56.98 s20468 (0.471) 1 47 NPR2
2 2 111.72–112.11 s29378 (0.426) 2 5
3 2 246.07–246.46 s01865 (0.427) 1 8 CHRNG
4 3 141.36–141.61 OAR3_141586525 (0.421) 1 14 HOX gene cluster
5 3 164.38–165.45 OAR3_165009241 (0.502) 2 4 HMGA2, MSRB3
6 5 105.87–105.93 s36709 (0.427) 1 1
7 6 40.21–42.53 OAR6_40277406 (0.421) 1 18 ABCG2, PDK2
8 6 76.38–76.86 OAR6_76473607 (0.499) 1 3 KIT
9 6 103.41–103.99 s21552 (0.419) 1 7 FGF5
10 7 49.12–49.22 s69881 (0.441) 1 1
11 7 97.3–97.72 OAR7_97378846 (0.452) 1 5 TSHR
12 8 34.2–35.35 s20065 (0.428) 1 6 BVES
13 8 67.47–67.84 OAR8_67529714 (0.436) 1 3
14 10 29.27–29.98 OAR10_29511510 (0.682) 6 3 RXFP2
15 10 30.6–30.79 s68983 (0.535) 3 2
16 11 18.57–19 OAR11_18701428 (0.535) 4 4 NF1
17 13 25.27–25.57 s71551 (0.534) 1 1
18 13 51.54–52.64 OAR13_51852034 (0.459) 1 1 BMP2
19 13 67.07–68.54 s51670 (0.664) 2 16 ASIP
20 13 84.89–84.98 s54638 (0.439) 1 1 NFATC2
21 16 41.74–42.43 OAR16_41943180 (0.422) 1 3 PRLR
22 17 64.75–64.89 s41543 (0.419) 1 0
23 18 19.65–20.23 s31152 (0.423) 1 3 ABHD2
24 18 40.36–40.58 s45597 (0.433) 1 2 FOXG1
25 19 7.41–7.6 s38567 (0.434) 1 3 GLB1
26 19 33.09–33.61 OAR19_33278780 (0.483) 1 1 MITF
27 19 55.99–56.25 s18532 (0.472) 1 2 CCR2
28 20 18.06–18.36 OAR20_18263165 (0.43) 1 4 VEGFA
29 21 45.19–45.58 s11631 (0.492) 2 6 OR2AG1
30 25 6.82–7.61 s03686 (0.573) 3 4
31 25 29.03–29.19 s10489 (0.464) 1 3 CDH23

A total of 31 genomic regions contained the top 0.1% of SNP ranked using global F ST (47 SNP). The top 5% of SNP were used to define the boundaries of each region using a stepping approach (see Materials and Methods). The number of genes and number of top SNP (0.1%) are given for each region along with candidates for selection.