Table 1. Whole blood and plasma variables related to oxidative damage, iron status, DNA damage, and vitamin metabolism before, during, and after a 13-d saturation dive in humans1.
Whole blood | Pre-dive | MD7 | MD13 | R+0 | R+90 |
SOD4, U/g hemoglobin | 1728±202a | 1645±70ac | 1218±190b | 1280±242b | 1313±115bc |
GPX, U/g hemoglobin | 50±11 | 50±10 | 49±11 | 51±11 | 59±9 |
White blood cell count, 109/L | 6.1±0.7 | 6.9±1.1 | 6.5±0.9 | 6.8±1.1 | 5.9±1.1 |
RBC count, 1012/L | 4.7±0.2 | 4.8±0.3 | 4.3±0.9 | 4.7±0.3 | 4.8±0.1 |
Hematocrit, % | 42.8±2.7 | 43.4±3.9 | 39.2±9.4 | 41.9±4.0 | 44.7±2.2 |
Hemoglobin, g/L | 147±8 | 148±12 | 135±30 | 145±12 | 151±7 |
Platelet count, 109/L | 203±46 | 209±37 | 201±71 | 200±36 | 197±27 |
PAR3, pg/107 cells | 81±8a | 95±16a | 122±21ac | 176±70bc | |
PAR2, pg/µg actin | 21±4a | 25±6ac | 30±7ac | 40±17bc | |
Plasma | |||||
Catalase2, µmol ⋅ min−1⋅ L−1 | 39±18a | 51±29ab | 71±10b | 42±21ab | 48±13ab |
3-Nitrotyrosine3, nmol/L | 0.2±0.1a | 0.2±0.1ab | 0.1±0.0ab | 0.0±0.0b | 0.1±0.0ab |
Advanced oxidation protein products, µmol/L | 301±74 | 375±125 | 303±61 | 311±111 | 201±92 |
Data are means ± SD, n = 6.
Significant effect of time, 2 P<0.05, 3 P<0.01, 4 P<0.001.
In each row, means without a common letter differ (P<.05) after a post hoc Bonferroni t test.