. 2012 Feb 7;7(2):e31058. doi: 10.1371/journal.pone.0031058

Table 2. Serum variables related to oxidative damage, iron status, DNA damage, and vitamin metabolism before, during, and after a 13-d saturation dive in humans¹.

	Pre-dive	MD7	MD13	R+0	R+90
Total antioxidant capacity, mmol/L	1.7±0.1	1.7±0.1	1.6±0.1	1.6±0.1	1.7±0
Total lipid peroxides, µmol/L	0.40±0.10	0.50±0.16	0.49±0.08	0.44±0.10	0.46±0.08
Erythropoietin⁴, U/L	6.8±1.7^a	2.0±0.9^b	3.5±1.9^b	6.5±5.3^a	6.3±1.9^a
Iron², µmol/L	21±6	22±9	25±4	25±3	16±3
Folate, nmol/L	39±8	40±8	38±7	44±20	42±9
Hepcidin³, µg/L	31.1±8.6^ab	28.3±9.2^b	27.9±8.6^b	27.9±8.5^b	33.5±9.4^a
Total iron-binding capacity², µmol/L	55±5^ab	53±4^a	50±4^b	52±4^ab	54±5^ab
Transferrin saturation³, %	38±12^ab	41±18^ab	51±11^a	48±7^a	29±6^b
Ferritin⁴, pmol/L	246±78^a	369±103^b	485±121^c	494±127^c	151±53^d
Transferrin⁴, g/L	2.45±0.19^a	2.44±0.21^a	2.25±0.17^b	2.32±0.21^a	2.45±0.25^a
Transferrin receptors³, mg/L	4.0±0.8^a	4.0±0.7^a	3.3±0.6^b	3.7±1.0^a	4.5±1.0^a
Estimated body iron⁴, mg/kg	10±2^a	12±1^b	14±1^c	13±1^c	8±2^d
Selenium, µmol/L	2.21±0.12	2.21±0.15	2.11±0.15	2.27±0.16	2.11±0.14
HMGB1, µg/L	22±4	25±10	18±5	16±2	17±3
Bilirubin, µmol/L	7±2	8±1	7±2	6±2	7±2
Haptoglobin, g/L	1.01±0.66	1.19±0.57	1.22±0.50	1.26±0.48	0.88±0.59
2-Methylcitric acid², nmol/L	158±41^a	182±49^ab	200±22^b	184±39^ab	167±34^ab
MMA², nmol/L	145±20^ab	146±23^ab	138±24^a	168±15^b	162±22^ab
Cystathionine, nmol/L	124±37	112±34	124±26	144±31	124±43
Homocysteine, µmol/L	7.5±1.0	8.2±1.6	7.4±0.9	7.3±1.1	7.1±2.0
MCH, pg/cell	31.1±1.0	30.8±0.8	31.1±0.6	30.8±0.7	31.3±0.7
MCHC, g/L	344±3	342±3	347±9	346±5	338±3
MCV⁴, fL	90.4±3.3^ac	90.2±3.0^ac	89.6±3.8^ab	88.9±3.4^b	92.5±2.9^c
RBC folate⁴, nmol/L	1466±331^a	1289±284^ac	1039±291^b	1116±291^bc	1422±218^ac
Vitamin B12⁴, pmol/L	424±72^a	494±64^b	489±82^b	484±90^b	452±52^c

Data are means ± SD, n = 6.

^2,3,4

Significant effect of time, ² P<0.05, ³ P<0.01, ⁴ P<0.001.

In each row, means without a common letter differ (P<.05) after a post hoc Bonferroni t test.

Table 2. Serum variables related to oxidative damage, iron status, DNA damage, and vitamin metabolism before, during, and after a 13-d saturation dive in humans1.

Table 2. Serum variables related to oxidative damage, iron status, DNA damage, and vitamin metabolism before, during, and after a 13-d saturation dive in humans¹.