Figure 4. Effect of disruption of NF-κB p50 on Th2 differentiation of naïve CD4 T-cells treated with IL-18.

CD4⁺ T-cells from Wild-type (WT) and NF-κB p50^−/− mice were cultured with IL-18 in the differentiation phase, restimulated with con A, and secretion of IL-4 (A), IL-5 (B) and IL-13 (C) was quantified by ELISA. n = 5−7 per group.