Table 3.

HIV-1 Protease Cleavage Sites

Site	AA	Position	References
gag
MA/CA	SQNY/PIV	1187–1188	Mammano et al., 1998, Cote et al., 2001
CA/p2	ARVL/AEA	1880–1881	Mammano et al., 1998, Cote et al., 2001
p2/NC	ATIM/MQR	1920–1921	Mammano et al., 1998), Cote et al., 2001
NC/p1	RQAN/FLG	2085–2086	Mammano et al., 1998), Cote et al., 2001, Zhang et al., 1997, Bally et al., 2000
p1/p6	PGNF/LQS	2136–2137	Mammano et al., 1998, Cote et al., 2001, Bally et al., 2000, Doyon et al., 1996
pol
TF/PRSF	SV/PQI	2257–2258	Cote et al., 2001
PR/RT	TLNF/PIS	2552–2553	Cote et al., 2001
RT (p51/p66)	AETF/YVD	3869–3870	Cote et al., 2001
RT/IN	RKVL/FLD	4232–4233	Cote et al., 2001

MA - Matrix

CA - Capsid

NC - Nucleocapsid

TF - Transframe

PR- Protease

RT- Reverse Transcriptase

IN - Integrase.

Scissile bonds are indicated by the slashes in the amino acid sequence.

Nucleic acid positions in relation to HXB2 (GenBank accession No. K03455) are indicated in the Position column.