In vivo comparison between conventional and super STE methods. (A) Metabolite amplitudes for conventional STEAM (Fig. 1A) and super-STEAM encoding (Fig. 1B, sech 180°, ΔT = 1.65ms, N = 12), normalized by the measured polarization, in a normal rat. The least-squares linear fits show the metabolite amplitude correlation between the two experiments, demonstrating that the contrast was similar. (B) STEAM (90°-90°) and super-STEP metabolite amplitudes (b = beff = 9.95 s/mm2), normalized by polarization, in a normal mouse. Again, the linear fits show reasonable correlation. Using the super-STEAM encoding and super-STEP approaches had significantly increased SNR.