Table 3.
Gender differences in glucose regulation in young adults with very low birth weight
| Men (n=42) | Women (n=69) | p Value | |
| Hyperglycaemia | 11 (26.2) | 10 (14.5) | 0.127 |
| Diabetes | 0 | 1 | |
| IGT | 2 | 4 | |
| IFG | 1 | 0 | |
| Non-diabetes/IGT/IFG with elevated 1 h glucose levels* | 8 | 5 | |
| HbA1c (%) | 5.39 (5.31 to 5.47) | 5.39 (5.31 to 5.47) | 0.635 |
| HOMA-β | 72.5 (59.0 to 86.0) | 103 (87.2 to 119.6) | 0.001 |
| HOMA-IR | 1.4 (1.14 to 1.69) | 1.6 (1.29 to 1.90) | 0.477 |
| Variable during OGTT | |||
| Insulinogenic index | 1.1 (0.64 to 1.60) | 1.4 (1.18 to 1.71) | 0.002 |
| GlucoseAUC (mmol/l × h) | 18.8 (17.9 to 19.7) | 18.2 (17.3 to 19.0) | 0.089 |
| InsulinAUC (μU/ml × h) | 135.3 (98.7 to 171.9) | 145.1 (121.7 to 168.6) | 0.052 |
| Reactive hypoglycaemia | 17 (40) | 17 (25) | 0.079 |
*
Defined as 1 h glucose levels >8.6 mmol/l.
HbA1c, haemoglobin A1c; HOMA-IR, homeostasis model of assessment for insulin resistance; HOMA-β, homeostasis model of assessment for beta cell; IFG, impaired fasting glycaemia; IGT, impaired glucose tolerance; OGTT, oral glucose tolerance test.
Data are expressed as mean (95% CI) or n (%).