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. 2012 Feb 7;2:250. doi: 10.1038/srep00250

Figure 6. GH-dependent alteration of olfactory bulb neurogenesis.

Figure 6

(A) No significant difference was apparent in the number of BrdU+ve cells detected in the OB 28 days after the 7-day ICV infusion of either GH or saline. In contrast, a significantly greater number of BrdU+ve/NeuN+ve cells was detected in the OB of GH- versus saline-infused mice (1455±37 vs. 869±140, p = 0.008, n = 3). (B) Significantly fewer BrdU+ve cells were detected in the OB of GH-infused mice following irradiation as compared to saline-infused controls (62±5 vs. 273±50, p = 0.007, n = 3). Likewise, the number of BrdU+ve/NeuN+ve cells detected in the OB of GH- versus saline-infused controls was also significantly reduced (21±4 vs. 63±12, p = 0.014, n = 3). **p<0.01.