Table 2.

Table of biochemical indices of the Control group, Low Dose group (LD=2000 mg/kg b.w.) and High Dose group (HD=5000 mg/kg b.w.) on day 15 after administration of P. niruri aqueous leaf extract on Sprague-Dawley rats on day 1.

Variable		Control	LD	HD	p-value
URE	mmol/l	7.6±1.1	8.1±2.1	8.7±2.3	NS
CR	µmol/l	67.9±9.7	59.4±17.2	56.5±17.3	NS
TP	g/l	60.1±5.3	57.4±15.5	55.0±15.6	NS
ALB	g/l	36.6±2.8	35.0±9.4	33.8±9.5	NS
GB	g/l	23.5±2.6	22.4±6.1	21.2±6.1	NS
DBIL	µmol/l	1.2±0.6	0.7±0.5	1.1±0.6	NS
IBIL	µmol/l	0.9±0.4	0.3±0.1	1.1±1.3	NS
TBIL	µmol/l	2.1±0.7	0.5±0.1	2.2±1.4	NS
GGT	U/l	1.4±0.7	1.9±0.7	1.1±0.7	NS
ALT	U/l	129±20	114±34	107±36	NS
AST	U/l	159±42	144±44	159±46	NS
ALP	U/l	444±36	388±136	420±127	NS

NS=Not Significant; URE=urea; CR= creatinine; TP=total protein; ALB=albumin; GB=globulin; DBIL=direct bilirubin; IBIL=indirect bilirubin; TBIL=total bilirubin; GGT=γ-glutamyltranspeptidase; ALT=alanine aminotransferase; AST=aspartate aminotransferase; ALP=alkaline phosphatase