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Periventricular leukomalacia was found in the parieto-occipital region of the patient's brain with Haddad syndrome (a, ×4). Focal necrosis (a) was noted in the white matter (arrow) close to the lateral ventricle (vent) which was characterized histologically by macrophages and reactive astrocytes (b, ×40). Hematoxylin-and-eosin
