Figure 3.

(A–D) EGFP mobility into and out of chromatin (as found from the maximum of the derived pair-correlation profile for these two diffusive routes) for the four distinct nuclear stages identified in Fig. 1 (early mitosis, mid-mitosis, late mitosis, and early interphase). The gray points correspond to EGFP mobility into the chromatin, and the black points correspond to EGFP mobility out of the chromatin for two different experiments. (A) In early mitosis, mobility into and out of the chromatin occurs with a 8 ± 5 ms delay. (B) In mid-mitosis, mobility into and out of the chromatin occurs with a 32 ± 8 ms delay. (C) In late mitosis, mobility into and out of the chromatin occurs with delays of 26 ± 6 ms and 141 ± 14 ms, respectively. Scale bar: 3 μm.