Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Maximum/pain-free walking distance
Systematic review	195 people with intermittent claudication Data from 1 RCT	Mean increase in pain-free walking distance 181 metres with prostaglandin E1 (PGE1) 104 m with pentoxifylline	Reported as significant but no further details given	Effect size not calculated	PGE1
Systematic review	82 people with intermittent claudication Data from 1 RCT	Mean increase in pain-free walking distance 106 m with PGE1 71 m with pentoxifylline	Reported as significant but no further details given	Effect size not calculated	PGE1
Systematic review	195 people with intermittent claudication Data from 1 RCT	Mean increase in maximal walking distance 213 m with PGE1 191 m with pentoxifylline	Reported as significant but no further details given	Effect size not calculated	PGE1