Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Arterial occlusion
Systematic review	2810 people Data from 1 RCT	Arterial occlusion or revascularisation procedures 3 months with aspirin with placebo Absolute results not reported	OR 0.46 95% CI 0.27 to 0.77	Moderate effect size	Antiplatelet agents (aspirin)
Systematic review	356 people undergoing peripheral endovascular intervention 2 RCTs in this analysis	Rates of restenosis or reocclusion 6 months with low-dose aspirin plus dipyridamole with placebo Absolute results not reported	OR 0.69 95% CI 0.44 to 1.10		Not significant
Systematic review	966 people 6 RCTs in this analysis	Proportion of people with arterial occlusion of either venous or artificial peripheral bypass grafts 12 months 114/501 (23%) with antiplatelet agents (aspirin or aspirin plus dipyridamole) 156/465 (34%) with placebo	OR 0.59 95% CI 0.45 to 0.79	Small effect size	Antiplatelet agents (aspirin or aspirin plus dipyridamole)
Systematic review	222 people 4 RCTs in this analysis Subgroup analysis	Proportion of people with arterial occlusion of artificial peripheral bypass grafts 12 months 21/115 (18%) with antiplatelet agents (aspirin or aspirin plus dipyridamole) 57/107 (53%) with placebo	OR 0.22 95% CI 0.12 to 0.38	Moderate effect size	Antiplatelet agents (aspirin or aspirin plus dipyridamole)
Systematic review	642 people 2 RCTs in this analysis Subgroup analysis	Proportion of people with arterial occlusion of venous peripheral bypass grafts 12 months 71/335 (21%) with antiplatelet agents (aspirin or aspirin plus dipyridamole) 86/307 (28%) with placebo	OR 0.68 95% CI 0.48 to 0.99 Result is of borderline significance	Small effect size	Antiplatelet agents (aspirin or aspirin plus dipyridamole)
Systematic review	3226 people with intermittent claudication, or having bypass surgery of the leg, or peripheral artery angioplasty 14 RCTs in this analysis	Arterial occlusion 19 months with antiplatelet agents with placebo or no additional treatment Absolute results not reported	RRR 37% P <0.00001	Effect size not calculated	Antiplatelet agents
Systematic review	1302 people 2 RCTs in this analysis	Arterial occlusion or revascularisation procedures up to 7 years with ticlopidine with placebo Absolute results not reported	OR 0.62 95% CI 0.41 to 0.93	Small effect size	Antiplatelet agents (ticlopidine)