Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Recurrence | |||||
[109]
Systematic review |
30 people Data from 1 RCT |
Recurrence
after 18 months
5% with surgery plus compression stockings 24% with compression stockings alone Absolute numbers not reported |
RR 0.21 95% CI 0.03 to 0.80 The RCT was poorly controlled, and its results should be interpreted with caution |
Moderate effect size | surgery plus compression stockings |
[92]
RCT |
45 people |
Recurrence rates
over 3 years
2/21 (10%) with minimally invasive surgery 9/24 (38%) with compression bandages |
P <0.05 The RCT randomised legs rather than people |
Effect size not calculated | surgery |
[95]
RCT |
428 people |
Recurrence rates
after 12 months
12% with superficial vein surgery plus compression 28% with compression alone Absolute numbers not reported |
HR –2.76 95% CI –4.27 to –1.78 |
Effect size not calculated | surgery plus compression |
[96]
RCT |
People with leg ulcers Further report of reference [95] |
Recurrence rates
3 years
31% with superficial vein surgery plus compression 56% with compression alone Absolute numbers not reported |
Reported as significant P <0.01 |
Effect size not calculated | surgery plus compression |
[93]
RCT |
170 people |
Recurrence rates
27 months
22% with subfascial endoscopic perforator surgery plus compression 23% with compression alone Absolute results reported graphically |
Reported as not significant |
Not significant |