Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
[110] RCT	39 people Further report of reference [97]	Adverse effects with open surgery with subfascial endoscopic perforator surgery (SEPS) Absolute numbers not reported	Significance not assessed
[98] RCT	People with leg ulcers	Wound infection rates 53% with open surgery 0% with SEPS Absolute numbers not reported	P <0.001	Effect size not calculated	SEPS