Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
RCT	342 people, all treated with antibiotics	Adverse effects 36% with super-colonisation with Streptococcus 33% with placebo Absolute numbers not reported	Reported as equally tolerated P value not reported The authors suggested that the high rates of apparent adverse effects found in both groups were likely to be associated with the condition being treated		Not significant