Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Symptom severity
[115] RCT	74 children and adolescents aged 7 to 17 years with GAD, separation anxiety disorder, and/or social phobia (47/74 [64%] had GAD either with or without another disorder) In review [114]	Proportion of people who were much or very much improved (defined as Clinical Global Impression-Improvement [CGI-I] score 2 or less) 22/36 (61%) with fluoxetine 13/37 (35%) with placebo	P = 0.03	Effect size not calculated	fluoxetine
[115] RCT	46 children and adolescents aged 7 to 17 years with GAD, either with or without another disorder In review [114]	Proportion of people with CGI-I score 2 or less 61% with fluoxetine (20 mg/day) 36% with placebo Absolute results not reported	P = 0.04	Effect size not calculated	fluoxetine