Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Quality of life
[64] RCT	373 people	Quality of Life Enjoyment and Satisfaction Questionnaire (mean change from baseline) 12 weeks 9% with sertraline (dose titrated from 25 mg/day in the first week to 50–150 mg/day by week 12) 2% with placebo Absolute numbers not reported	P <0.0001	Effect size not calculated	sertraline