Fig. 5.

Fxr hematoxylin and eosin mice have increased expression of genes involved in energy expenditure in skeletal muscle and increased fat absorption. Female wild-type (WT) and Fxr hematoxylin and eosin mice were fed a high-fat diet for 14 wk (n = 8 mice per group). A and C, The mRNA levels of genes in the liver (A) and skeletal muscle (C) were determined by qRT-PCR. B, Hepatic triglyceride levels were quantified. D, Intestinal fat absorption was determined after injection of [¹⁴C]triolein and tyloxapol. *, P < 0.05; #, P < 0.01.