Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Adverse effects | |||||
Systematic review |
39 women randomised Data from 1 RCT |
Proportion of women who had a preterm birth
8/12 (67%) with prednisolone plus low-dose aspirin 3/22 (14%) with aspirin alone |
RR 4.9 95% CI 1.6 to 15.1 |
Moderate effect size | aspirin alone |
Systematic review |
39 women randomised Data from 1 RCT |
Mean birth weight
2800 g with prednisolone plus low-dose aspirin 3352 g with aspirin alone |
Mean difference in birth weight 552 g 95% CI 1064 g to 39 g |
Moderate effect size | aspirin alone |