Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Mortality
[78] Systematic review	87 people with severe daytime hypoxaemia Data from 1 RCT	Mortality 5 years 19/42 (45%) with domiciliary daily oxygen supplementation 30/45 (67%) with no oxygen supplementation	RR 0.68 95% CI 0.46 to 1.00	Small effect size	domiciliary daily oxygen supplementation
[78] Systematic review	163 people with mild to moderate hypoxaemia (PaO2 56–65 mmHg or >55 mmHg) 2 RCTs in this analysis	Mortality 36 to 85 months 42/82 (51%) with domiciliary daily oxygen supplementation 35/81 (43%) with no oxygen supplementation	RR 1.18 95% CI 0.86 to 1.63		Not significant