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. 2011 Jun 6;2011:1502.
Ref (type) Population Outcome, Interventions Results and statistical analysis Effect size Favours
Quality of life
[97]
Systematic review		 618 people
11 RCTs in this analysis		 Difference in fatigue component of Chronic Respiratory Disease Questionnaire (CRQ)
with pulmonary rehabilitation
with usual care
Absolute results not reported
WMD 0.92
95% CI 0.71 to 1.13
The effect was larger than the minimally clinically important difference of 0.5 units 		Effect size not calculated pulmonary rehabilitation
[104]
RCT		 39 people with COPD Mean difference in fatigue component of CRQ 8 weeks
from 9.8 to 17.4 (+7.6) with home-based pulmonary rehabilitation
from 11.6 to 13.2 (+1.6) with control
P <0.004 		Effect size not calculated home-based pulmonary rehabilitation
[97]
Systematic review		 618 people
11 RCTs in this analysis		 Difference in emotional function component of CRQ
with pulmonary rehabilitation
with usual care
Absolute results not reported
WMD 0.76
95% CI 0.52 to 1.00
The effect was larger than the minimally clinically important difference of 0.5 units 		Effect size not calculated pulmonary rehabilitation
[104]
RCT		 39 people with COPD Mean difference in emotional function component of CRQ 8 weeks
from 22.1 to 33.5 (+11.4) with home-based pulmonary rehabilitation
from 27.0 to 29.7 (+2.7) with control
P <0.008 		Effect size not calculated home-based pulmonary rehabilitation
[97]
Systematic review		 618 people
11 RCTs in this analysis		 Difference in mastery component of CRQ
with pulmonary rehabilitation
with usual care
Absolute results not reported
WMD 0.97
95% CI 0.74 to 1.20
The effect was larger than the minimally clinically important difference of 0.5 units 		Effect size not calculated pulmonary rehabilitation
[102]
RCT		 54 people with mild to moderate COPD (FEV1 30–80% predicted) Difference in symptoms domain of St George's Respiratory Questionnaire (SGRQ) from baseline 8 weeks
from 60 to 38 (–22) with pulmonary rehabilitation
from 60 to 46 (–14) with control
P <0.05 		Effect size not calculated pulmonary rehabilitation
[102]
RCT		 54 people with mild to moderate COPD (FEV1 30–80% predicted) Difference in activity domain of SGRQ from baseline 8 weeks
from 67 to 43 (–24) with pulmonary rehabilitation
from 70 to 67 (–3) with control
P <0.05 		Effect size not calculated pulmonary rehabilitation
[102]
RCT		 54 people with mild to moderate COPD (FEV1 30–80% predicted) Difference in impact domain of SGRQ from baseline 8 weeks
from 36 to 17 (–19) with pulmonary rehabilitation
from 33 to 33 (no change) with with control
P <0.05 		Effect size not calculated pulmonary rehabilitation
[100]
RCT		 24 people with severe COPD Difference in symptoms domain of SGRQ from baseline 8 weeks
from 51 to 40 (–11) with pulmonary rehabilitation
from 50 to 49 (–1) with control
P <0.05 		Effect size not calculated pulmonary rehabilitation
[100]
RCT		 24 people with severe COPD Difference in activity domain of SGRQ from baseline 8 weeks
from 75 to 63 (–12) with pulmonary rehabilitation
from 75 to 79 (+4) with control
P <0.05 		Effect size not calculated pulmonary rehabilitation
[100]
RCT		 24 people with severe COPD Difference in impact domain of SGRQ from baseline 8 weeks
from 47 to 37 (–10) with pulmonary rehabilitation
from 49 to 45 (–4) with control
P >0.05 		Not significant
[101]
RCT		 30 people with COPD Difference in symptoms domain of SGRQ from baseline 12 weeks
+10.6 with pulmonary rehabilitation
–0.5 with control
Significance not assessed
[101]
RCT		 30 people with COPD Difference in activity domain of SGRQ from baseline 12 weeks
+2.5 with pulmonary rehabilitation
+2.7 with control
Significance not assessed
[101]
RCT		 30 people with COPD Difference in impact domain of SGRQ from baseline 12 weeks
+9.7 with pulmonary rehabilitation
+3.4 with control
Significance not assessed
[103]
Systematic review		 269 people with COPD
3 RCTs in this analysis		 Difference in health-related quality of life (HRQL) anxiety score 12 months
with pulmonary rehabilitation
with standard care
Absolute numbers not reported
SMD –0.33
95% CI –0.57 to –0.09
P = 0.008 		Effect size not calculated pulmonary rehabilitation
[103]
Systematic review		 269 people with COPD
3 RCTs in this analysis		 Difference in depression score 12 months
with pulmonary rehabilitation
with standard care
Absolute numbers not reported
SMD –0.58
95% CI –0.93 to –0.23
P = 0.001 		Effect size not calculated pulmonary rehabilitation
[100]
RCT		 24 people with severe COPD Change in Beck Depression Inventory 8 weeks
from 14 to 6 (–8) with pulmonary rehabilitation
from 18 to 16 (–2) with control
P <0.01 		Effect size not calculated pulmonary rehabilitation
[100]
RCT		 24 people with severe COPD Change in State Trait Anxiety Inventory 8 weeks
from 9 to 8 (–1) with pulmonary rehabilitation
from 19 to 21 (+2) with control
P >0.05 		Not significant