Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Lung function
[106] Systematic review	Number of people not reported 6 RCTs in this analysis	Inspiratory muscle strength with inspiratory muscle training (IMT) plus general exercise reconditioning with general exercise reconditioning alone Absolute results not reported	WMD 0.47 cm H2O 95% CI 0.15 cm H2O to 0.79 cm H2O	Effect size not calculated	IMT plus general exercise reconditioning
[106] Systematic review	Number of people not reported; subgroup analysis of people with inspiratory muscle weakness at baseline 3 RCTs in this analysis	Inspiratory muscle strength with IMT plus general exercise reconditioning with general exercise reconditioning alone Absolute results not reported	WMD +16 cm H2O (CI not reported) P <0.001	Effect size not calculated	IMT plus general exercise reconditioning
[106] Systematic review	Number of people not reported; subgroup analysis of people without inspiratory muscle weakness at baseline 3 RCTs in this analysis	Inspiratory muscle strength with IMT plus general exercise reconditioning with general exercise reconditioning alone Absolute results not reported	WMD –3 cm H2O (CI not reported) P = 0.54		Not significant
[106] Systematic review	Number of people not reported 3 RCTs in this analysis	Inspiratory muscle endurance with IMT plus general exercise reconditioning with general exercise reconditioning alone Absolute results not reported	WMD 0.55 seconds 95% CI 0.14 seconds to 0.97 seconds	Effect size not calculated	IMT plus general exercise reconditioning
Exercise capacity
[106] Systematic review	Number of people not reported 4 RCTs in this analysis	Functional exercise capacity (6- or 12-minute walk test) with IMT plus general exercise reconditioning with general exercise reconditioning alone Absolute results not reported	WMD +0.20 m 95% CI –0.21 m to +0.61 m		Not significant