Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Quality of life
[32] Systematic review	6453 people with COPD 14 RCTs in this analysis	Mean change in St George's Respiratory Questionnaire 1 to 36 months with long-acting beta2 agonist (salmeterol or formoterol) with placebo Absolute numbers not reported	WMD –3.26 95% CI –4.57 to –1.96	Effect size not calculated	long-acting beta2 agonist