Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Wound infections in adults
Systematic review	4904 adults 40 RCTs in this analysis	Proportion of people with wound infections 89/2481 (4%) with laparascopic surgery 178/2423 (7%) with open surgery	OR 0.45 95% CI 0.35 to 0.58	Moderate effect size	laparascopic surgery
Systematic review	3686 people 25 RCTs in this analysis	Proportion of people with wound infections 64/1713 (4%) with laparoscopic surgery 133/1973 (7%) with open surgery	OR 0.52 95% CI 0.39 to 0.70 P <0.0001	Small effect size	laparoscopic surgery
RCT	50 adults with acute appendicitis	Proportion of people with wound/port site infections 0/25 (0%) with laparoscopic surgery 1/25 (4%) with open surgery	P >0.05		Not significant