Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Postoperative ileus
RCT	735 people aged 14 to 91 years with complicated appendicitis or simple appendicitis	Proportion of people with postoperative adhesive ileus 6/374 (1.6%) with double invagination (purse string with Z stitch) 1/361 (0.3%) with simple ligation	P <0.05	Effect size not calculated	simple ligation
RCT	134 people aged 4 to 90 years	Proportion of people with postoperative adhesive ileus 1/55 (2%) with double invagination 0/79 (0%) with simple ligation	P value not reported Reported as not significant		Not significant
Postoperative fever
RCT	735 people aged 14 to 91 years with complicated appendicitis or simple appendicitis	Proportion of people with postoperative fever 16.3% with double invagination (purse string with Z stitch) 16.1% with simple ligation Absolute numbers not reported	P value not reported Reported as not significant		Not significant