Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Breast pain
RCT	145 premenopausal women with cyclical breast pain	Reduction in mean breast pain score (visual analogue score where 0 = no pain and 100 = worst pain) 3 months 59.5 to 11.7 with gestrinone 2.5 mg twice weekly 58.2 to 36.7 with placebo	P <0.0001	Effect size not calculated	gestrinone