Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Breast pain
RCT	147 premenopausal women with breast pain	Mean days with severe breast pain per cycle (pain measured using Cardiff breast pain chart) 6 months 17.6 to 5.9 (67% reduction from baseline) with goserelin injection 18.4 to 12.0 (35% reduction from baseline) with placebo injection	P = 0.0001	Effect size not calculated	goserelin injection