Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Degree of discomfort
RCT	54 men In review	Degree of discomfort score 240 days –1.1 with allopurinol 300 and 600 mg combined +0.2 with placebo	P = 0.02	Effect size not calculated	allopurinol