Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
[74] Systematic review		Adverse effects with dihydropyridine calcium channel blockers with placebo
[75] Systematic review		Adverse effects with diltiazem with placebo
[76] RCT	2590 people with New York Heart Association (NYHA) functional class II to IV heart failure	Rate of mortality in people taking digoxin, class I or II antiarrhythmics, amiodarone, or drugs associated with torsade de pointes with mibefradil with placebo Absolute results reported graphically	Reported as significant P value not reported	Effect size not calculated	placebo