Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Death or hospital admission
[113] RCT	988 people with New York Heart Association (NYHA) functional class I to IV heart failure and left ventricular ejection fraction (LVEF) >45% Subgroup analysis	Rate of combined primary outcome of hospital admission for heart failure, or heart failure mortality mean follow-up of 37 months with digoxin with placebo Absolute results not reported	HR 0.82 95% CI 0.63 to 1.07 P = 0.136		Not significant