Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Heart failure-specific re-admission to hospital | |||||
[30]
Systematic review |
12,763 people with left ventricular dysfunction or heart failure of mean duration 35 months 5 RCTs in this analysis |
Proportion of people admitted to hospital for heart failure causes
876/6391 (14%) with ACE inhibitors 1202/6372 (19%) with placebo |
OR 0.67 95% CI 0.61 to 0.74 See further information on studies for details of relative benefits of ACE inhibitors |
Small effect size | ACE inhibitors |
[30]
Systematic review |
5966 people at 1 year post-infarction 3 RCTs in this analysis |
Proportion of people admitted to hospital for heart failure causes
355/2995 (12%) with ACE inhibitors 460/2971 (16%) with placebo |
OR 0.73 95% CI 0.63 to 0.85 See further information on studies for details of relative benefits of ACE inhibitors |
Small effect size | ACE inhibitors |