Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Death or hospital admission
[32] RCT	3164 people with New York Heart Association (NYHA) functional class II to IV heart failure	Rate of combined outcome of death or hospital admission for any reason 1338/1596 (84%) with low-dose lisinopril (2.5 or 5.0 mg/day) 1250/1568 (80%) with high-dose lisinopril (32.5 or 35.0 mg/day)	ARR 4.1% CI not reported HR 0.88 95% CI 0.82 to 0.96	Small effect size	high-dose lisinopril
Heart failure-specific re-admission to hospital
[32] RCT	3164 people with NYHA functional class II to IV heart failure	Proportion of people admitted to hospital for heart failure 1576/1596 (99%) with low-dose lisinopril (2.5 or 5.0 mg/day) 1199/1568 (77%) with high-dose lisinopril (32.5 or 35.0 mg/day)	ARR 22.2% CI not reported P = 0.002	Effect size not calculated	high-dose lisinopril