Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Withdrawal | |||||
[32]
RCT |
3164 people with New York Heart Association (NYHA) functional class II to IV heart failure |
Proportion of people withdrawing from RCT
18% with low-dose lisinopril (2.5 or 5.0 mg/day) 17% with high-dose lisinopril (32.5 or 35.0 mg/day) Absolute numbers not reported |
Significance not assessed |
||
Adverse effects | |||||
[32]
RCT |
3164 people with NYHA functional class II to IV heart failure |
Proportion of people with dizziness
12% with low-dose lisinopril (2.5 or 5.0 mg/day) 19% with high-dose lisinopril (32.5 or 35.0 mg/day) Absolute numbers not reported |
Significance not assessed |
||
[32]
RCT |
3164 people with NYHA functional class II to IV heart failure |
Proportion of people with hypotension
7% with low-dose lisinopril (2.5 or 5.0 mg/day) 11% with high-dose lisinopril (32.5 or 35.0 mg/day) Absolute numbers not reported |
Significance not assessed |
||
[32]
RCT |
3164 people with NYHA functional class II to IV heart failure |
Proportion of people with worsening renal function
7% with low-dose lisinopril (2.5 or 5.0 mg/day) 10% with high-dose lisinopril (32.5 or 35.0 mg/day) Absolute numbers not reported |
Significance not assessed |
||
[32]
RCT |
3164 people with NYHA functional class II to IV heart failure |
Proportion of people with significant change in serum potassium concentration
7% with low-dose lisinopril (2.5 or 5.0 mg/day) 7% with high-dose lisinopril (32.5 or 35.0 mg/day) Absolute numbers not reported |
Significance not assessed |
||
[32]
RCT |
3164 people with NYHA functional class II to IV heart failure |
Proportion of people with cough
13% with low-dose lisinopril (2.5 or 5.0 mg/day) 11% with high-dose lisinopril (32.5 or 35.0 mg/day) Absolute numbers not reported |
Significance not assessed |