Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Ophthalmopathy
RCT 3-armed trial	114 people with hyperthyroidism caused by Graves' disease	Proportion of people with worsening ophthalmopathy 13/39 (33%) with radioiodine 6/37 (16%) with surgery	Between-group P value not reported P = 0.02 for radioiodine v surgery or medical antithyroid treatment combined	Effect size not calculated	surgery