Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Improvement in bulimia symptoms
Systematic review	44 people 2 RCTs in this analysis	Clinical improvement (at least 50% reduction in binge-eating episodes) after a mean of 11 weeks' treatment with tricyclic antidepressants (TCAs) with placebo Absolute results not reported	RR 0.29 95% CI 0.13 to 0.64	Moderate effect size	TCAs
Systematic review	121 people 3 RCTs in this analysis	Bulimic symptoms after a mean of 11 weeks' treatment with TCAs with placebo Absolute results not reported	SMD –0.75 95% CI –1.12 to –0.38	Effect size not calculated	TCAs
Remission
Systematic review	132 people 3 RCTs in this analysis	Absolute non-remission rates 79% with TCAs (desipramine, imipramine) 91% with placebo	RR 0.86 95% CI 0.70 to 1.07		Not significant
Depression
Systematic review	People with bulimia 3 RCTs in this analysis	Depressive symptoms with TCAs with placebo Absolute results not reported	Reported as not significant No further data reported		Not significant