Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Improvement in bulimia symptoms
RCT 4-armed trial	171 people In review	Mean reduction in number of binges a week 7.7 with imipramine plus CBT-BN 3.6 with imipramine 200 mg to 300 mg daily	Significance assessment not performed
RCT 3-armed trial	71 people In review	Bulimic symptoms at 24 weeks with CBT-BN plus desipramine with desipramine (mean 167 mg/day) Absolute results not reported	SMD +0.10 95% CI –0.70 to +0.90		Not significant
Remission
RCT 3-armed trial	71 people In review	Remission rate at 24 weeks 67% with CBT-BN plus desipramine 42% with desipramine (mean 167 mg/day) Absolute numbers not reported	RR 1.75 95% CI 0.69 to 4.44		Not significant