Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Improvement in bulimia symptoms
RCT 4-armed trial	171 people In review	Mean reduction in number of binges a week 7.7 with imipramine plus CBT for bulimia nervosa (CBT-BN) 8.2 with CBT-BN plus placebo	P = 0.67		Not significant
RCT 3-armed trial	71 people In review	Bulimic symptoms after 24 weeks with CBT-BN plus desipramine with CBT-BN alone Absolute results not reported	SMD +0.09 95% CI –0.61 to +0.79		Not significant
Remission
RCT 3-armed trial	71 people In review	Remission rate after 24 weeks 67% with CBT-BN plus desipramine 44% with CBT-BN alone Absolute numbers not reported	RR 1.70 95% CI 0.71 to 4.07		Not significant