Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Total symptom severity
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Total symptom severity on a scale of 0 to 3 (0 = no symptoms, 3 = most severe) 4 weeks 0.8 with clobetasol propionate shampoo 0.05% used for 2.5 minutes 2.6 with vehicle shampoo (placebo)	P less than or equal to 0.02	Effect size not calculated	Clobetasol propionate 0.05% used for 2.5 minutes
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Total symptom severity, on a scale of 0 to 3 (0 = no symptoms, 3 = most severe) 4 weeks 0.6 with clobetasol propionate shampoo 0.05% used for 5 minutes 2.6 with vehicle shampoo (placebo)	P less than or equal to 0.02	Effect size not calculated	Clobetasol propionate 0.05% used for 5 minutes
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Total symptom severity, on a scale of 0 to 3 (0 = no symptoms, 3 = most severe) 4 weeks 0.7 with clobetasol propionate shampoo 0.05% used for 10 minutes 2.6 with vehicle shampoo (placebo)	P less than or equal to 0.02	Effect size not calculated	Clobetasol propionate 0.05% used for 10 minutes
Scalp scaling
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Loose scaling, on a scale from 0 to 3 (0 = clear, 3 = worst) 4 weeks with clobetasol propionate shampoo 0.05% for 2.5 minutes with vehicle shampoo (placebo) Absolute results not reported	Reported as not significant		Not significant
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Loose scaling, on a scale from 0 to 3 (0 = clear, 3 = worst) 4 weeks 0.4 with clobetasol propionate shampoo 0.05% for 5 minutes 1.0 with vehicle shampoo (placebo)	P = 0.051		Not significant
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Loose scaling, on a scale from 0 to 3 (0 = clear, 3 = worst) 4 weeks 0.3 with clobetasol propionate shampoo 0.05% for 10 minutes 1.0 with vehicle shampoo (placebo)	P = 0.027	Effect size not calculated	Clobetasol propionate 0.05% for 10 minutes
Scalp redness (erythema)
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Erythema, on a scale of 0 to 3 (0 = clear, 3 = worst) 4 weeks with clobetasol propionate shampoo 0.05% for 2.5 minutes with vehicle shampoo (placebo) Absolute numbers not reported	Reported as not significant		Not significant
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Erythema, on a scale of 0 to 3 (0 = clear, 3 = worst) 4 weeks 0.1 with clobetasol propionate shampoo 0.05% for 5 minutes 0.7 with vehicle shampoo (placebo)	P = 0.024	Effect size not calculated	Clobetasol propionate 0.05% for 5 minutes
RCT Crossover design 5-armed trial	55 people with scalp seborrhoeic dermatitis	Erythema, on a scale of 0 to 3 (0 = clear, 3 = worst) 4 weeks with clobetasol propionate shampoo 0.05% for 10 minutes with vehicle shampoo (placebo) Absolute results not reported	Reported as not significant		Not significant
Scalp itching
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Itching, measured on a 100-mm analogue scale (0 = no itching, 100 = worst) 4 weeks with clobetasol propionate shampoo 0.05% for 2.5 minutes with vehicle shampoo (placebo) Absolute results not reported	Reported as not significant		Not significant
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Itching, measured on a 100-mm analogue scale (0 = no itching, 100 = worst) 4 weeks 4.8 mm with clobetasol propionate shampoo 0.05% for 5 minutes 34.0 mm with vehicle shampoo (placebo)	P = 0.007
RCT 5-armed trial	55 people with scalp seborrhoeic dermatitis	Itching, measured on a 100-mm analogue scale (0 = no itching, 100 = worst) 4 weeks with clobetasol propionate shampoo 0.05% for 10 minutes with vehicle shampoo (placebo) Absolute results not reported	Reported as not significant		Not significant