Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Re-attachment rate
RCT	286 people; 286 eyes with rhegmatogenous retinal detachment (RRD) and proliferative vitreoretinopathy (PVR) of grade C2 or more; multicentre RCT; 24 surgeons	Retinal re-attachment rate (after 1 operation) 6 months 89/142 (63%) with daunorubicin 73/135 (54%) with no daunorubicin	OR 1.43 95% CI 0.88 to 2.30 P = 0.07		Not significant
RCT	286 people; 286 eyes with RRD and PVR of grade C2 or more; multicentre RCT; 24 surgeons	Overall re-attachment rate (with or without re-operation) 1 year 105/131 (80%) with daunorubicin 103/126 (82%) with no daunorubicin	Reported as not significant P value not reported		Not significant
RCT	30 people; 30 eyes with RRD and grade D1 PVR or more	Retinal re-attachment 3 months 13/15 (87%) with daunorubicin 10/15 (67%) with no daunorubicin	Reported as not significant P value not reported		Not significant