Table 1.
Intraoperative probes detecting malignant tissue
| Probes localizing malignancy (n=25) | ||||||||
|---|---|---|---|---|---|---|---|---|
| TBR | ≥1.5 | ≥2.0 | ≥2.5 | ≥3.0 | ||||
| Gamma probe | Sensitivity | 100.0 | Sensitivity | 100.0 | Sensitivity | 95.8 | Sensitivity | 91.7 |
| Specificity | 80.0 | Specificity | 80.0 | Specificity | 100.0 | Specificity | 100.0 | |
| PPV | 96.2 | PPV | 96.0 | PPV | 100.0 | PPV | 100.0 | |
| NPV | 100.0 | NPV | 100.0 | NPV | 83.3 | NPV | 71.4 | |
| Beta probe | Sensitivity | 100.0 | Sensitivity | 100.0 | Sensitivity | 100.0 | Sensitivity | 100.0 |
| Specificity | 60.0 | Specificity | 60.0 | Specificity | 100.0 | Specificity | 100.0 | |
| PPV | 92.6 | PPV | 92.6 | PPV | 100.0 | PPV | 100.0 | |
| NPV | 100.0 | NPV | 100.0 | NPV | 100.0 | NPV | 100.0 | |
This table demonstrates the overall ability of the probes to detect malignant tissue regardless of their sizes. As shown, both probes had excellent sensitivities between TBR of 2.5 and 3.0. The beta probe had a more definite cut off value of 2.5 than the gamma probe
PPV positive predictive value, NPV negative predictive value, n number of samples