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. 2011 Dec 6;153(2):759–769. doi: 10.1210/en.2011-1699

Fig. 1.

Fig. 1.

Two hormone replacement schedules were studied. A, For 4-d hormone replacement, rats (n = 6 rats per group) were given two injections of E2 (10 μg, sc), 24 h apart, followed by single P4 injection (4 mg/kg, sc) 24 h after last E2 injection. A single injection of BrdU (100 mg/kg, ip) was given 1 h after P4; tissue collection, 30 h after BrdU. B, For 30-d hormone replacement, rats (n = 5 rats per group) were implanted with E2 pellet (0.72 mg/30 d release) 2 wk after OVX, followed by P4 pellet (50 mg/15 d release) in the last 10 d; tissue collection on d 30.