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. 2011 Dec 6;153(2):759–769. doi: 10.1210/en.2011-1699

Fig. 3.

Fig. 3.

Regulation of Pgrmc1 and Pgr mRNA by E2 and P4. A, Pgrmc1 mRNA was increased by E2, P4, and E2+P4 in CA1, CA3, and DG neurons after both 4-d (n = 6 rats/group) and 30-d hormone replacement schedules (n = 5 rats per group). *, P < 0.03 compared with respective OVX. B, In CA1 neurons Pgr mRNA was increased by E2, P4, and E2+P4 on the 4-d schedule, and by E2 or P4 alone on the 30-d schedule. Modest increase in Pgr mRNA was also seen in CA3 neurons by P4 (P4 alone and E2+P4 group) only on the 4-d schedule. Pgr mRNA did not respond to either the 4-d or 30-d schedule in DG neurons. **, P < 0.01 vs. OVX in CA1. ^, P < 0.01 compared with 4-d schedule in CA1. *, P < 0.05, vs. OVX in CA3 neurons.