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PLX4720 induces tumor regression. A, Vehicle-treated mice had an exponential tumor growth up to 115 mm3 ± 14 mm3 by 35 d. No mouse in this group survived beyond 35 d. B, PLX4720-treated mice had tumor regression down to 14 mm3 ± 1 mm3 by 49 d. C, Tumor progression and regression (gross photos and GFP images). *, P < 0.05.
