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PLX4720 induces regression of lung metastases. Number of metastases/cm2 as detected by GFP imaging. A, Vehicle-treated mice had exponential growth in the number of metastases, whereas PLX4720-treated mice had a significant reduction in the number of metastases by 49 d (B); *, P < 0.05. C, Anterior projections of the lungs with GFP imaging and gross photos.
