Table 1.
Clinical Characteristics of the Study Population
| Entire cohort (n=3171) | Healthy referent cohort* (n=706) | |
|---|---|---|
| Age, yrs | 50.8 ± 10.3 | 45.6 ± 8.1 |
| Male gender, % | 1620 (51.1%) | 354 (50.1%) |
| Height, cm | 170.1 ± 9.7 | 171.0 ± 9.6 |
| BSA, m2 | 1.94 ± 0.25 | 1.85 ± 0.21 |
| BMI, kg/m2 | 27.8 ± 5.3 | 24.6 ± 2.9 |
| Obesity, % | 870 (27.5%) | - |
| Systolic blood pressure, mmHg | 122.2 ± 16.4 | 111.5 ± 9.1 |
| Diastolic blood pressure, mmHg | 76.1 ± 9.4 | 71.9 ± 7.2 |
| HTN, % | 941 (29.7%) | - |
| Smoking, % | ||
| Current | 417 (13.2%) | - |
| Former | 1231 (38.8%) | - |
| Never | 1523 (48.0%) | 706 (100.0%) |
| Smoking, pack-years | ||
| Current | 27.9 ± 18.8 | - |
| Former | 16.6 ± 17.1 | - |
| COPD, % | 159 (5.5%) | - |
| Hx of Pulmonary embolism, % | 22 (0.7%) | - |
| DM, % | 196 (6.2%) | - |
| Dyslipidemia, % | 761 (24.0%) | 82 (11.6%) |
| CVD, % | 183 (5.8%) | - |
| CHD, % | 118 (3.7%) | - |
| CHF, % | 9 (0.3%) | - |
| Valvular heart surgery, % | 1 (0.03%) | - |
| Dyspnea, % | 665 (20.9%) | 89 (12.6%) |
| Main pulmonary artery diameter (mPA), mm | 25.1 ± 2.8 | 24.7 ± 2.7 |
| Ratio main PA: ascending aorta diameter (ratio PA) | 0.77 ± 0.09 | 0.80 ± 0.09 |
BSA denotes body surface area; BMI, body mass index; HTN, hypertension; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; CVD, cardiovascular disease; CHD, coronary heart disease; and CHF, congestive heart failure.
*
Healthy referent cohort consisted of participants in the CT study free of obesity, HTN, current and past smokers, COPD, history of pulmonary embolism, DM, CVD, and prior heart valve surgery.