Table 4.
Clinical Characteristics as Stratified by 90th percentile sex-specific cutpoint for mPA and ratio PA >0.9.
| mPA >90th Percentile (n=438) | mPA ≤90th Percentile (n=2733) | P-value | Ratio PA >0.9 (n=226) | Ratio PA ≤0.9 (n=2945) | P-value | |
|---|---|---|---|---|---|---|
| Age, yrs | 52.8 ± 11.5 | 50.4 ± 10.1 | <0.001 | 44.8 ± 8.8 | 51.3 ± 10.3 | <0.001 |
| Male gender, % | 229 (52.3%) | 1391 (50.9%) | 0.59 | 120 (53.1%) | 1500 (50.9%) | 0.53 |
| Height, cm | 172.2 ± 9.9 | 169.8 ± 9.6 | <0.001 | 171.6 ± 9.7 | 170.0 ± 9.6 | 0.02 |
| BSA, m2 | 2.1 ± 0.3 | 1.9 ± 0.2 | <0.001 | 2.0 ± 0.3 | 1.9 ± 0.2 | 0.07 |
| BMI, kg/m2 | 30.6 ± 6.0 | 27.3 ± 5.0 | <0.001 | 27.9 ± 5.3 | 27.8 ± 5.3 | 0.74 |
| Obesity (%) | 198 (45.2%) | 672 (24.6%) | <0.001 | 61 (27.0%) | 809 (27.5%) | 0.87 |
| Systolic blood pressure, mmHg | 124.8 ± 18.0 | 121.8 ± 16.1 | <0.001 | 116.7 ± 14.1 | 122.4 ± 16.5 | <0.001 |
| Diastolic blood pressure, mmHg | 76.6 ± 9.2 | 76.0 ± 9.5 | 0.17 | 74.6 ± 9.0 | 76.2 ± 9.5 | 0.01 |
| HTN (%) | 170 (38.8%) | 771 (28.2%) | <0.001 | 45 (19.9%) | 896 (30.4%) | <0.001 |
| Smoking, % | ||||||
| Current | 48 (11.0%) | 369 (13.5%) | 22 (9.7%) | 395 (13.4%) | ||
| Former | 199 (45.4%) | 1032 (37.8%) | 0.01 | 67 (29.6%) | 1164 (39.5%) | <0.001 |
| Never | 191 (43.6%) | 1332 (48.7%) | 137 (60.6%) | 1386 (47.1%) | ||
| Smoking, pack-years | ||||||
| Current | 26.5 ± 15.7 | 28.1 ± 19.2 | 0.59 | 17.6 ± 11.5 | 28.5 ± 19.0 | 0.01 |
| Former | 18.5 ± 18.5 | 16.3 ± 16.8 | 0.11 | 11.8 ± 13.8 | 16.9 ± 17.2 | 0.02 |
| COPD (%) | 26 (5.9%) | 133 (4.9%) | 0.22 | 6 (2.7%) | 153 (5.2%) | 0.07 |
| Hx of Pulmonary embolism, % | 6 (1.4%) | 16 (0.6%) | 0.07 | 2 (0.9%) | 20 (0.7%) | 0.72 |
| DM, % | 49 (11.2%) | 147 (5.4%) | <0.001 | 12 (5.3%) | 184 (6.2%) | 0.57 |
| Dyslipidemia, % | 101 (23.1%) | 660 (24.1%) | 0.61 | 38 (16.8%) | 723 (24.6%) | 0.01 |
| CVD, % | 36 (8.2%) | 147 (5.4%) | 0.02 | 12 (5.3%) | 171 (5.8%) | 0.76 |
| CHD, % | 25 (5.7%) | 93 (3.4%) | 0.02 | 6 (2.7%) | 112 (3.8%) | 0.38 |
| CHF, % | 2 (0.5%) | 7 (0.3%) | 0.46 | 1 (0.4%) | 8 (0.3%) | 0.64 |
| Valvular Heart Surgery, % | 0 (0.0%) | 1 (0.0%) | 0.69 | 0 (0.0%) | 1 (0.0%) | 0.78 |
| Dyspnea, % | 110 (25.1%) | 555 (20.3%) | 0.02 | 47 (20.8%) | 618 (21.0%) | 0.99 |
Abbreviations as in Table 1.