Table 5.
MLH1 missense mutations analyzed by SIFT.
| Sequence variant | Structural alteration | SIFT scores | Prediction |
|---|---|---|---|
| 649C>T | R217C | 0.00 | Intolerant |
| 655 A>G | I219V | 0.57 | Tolerated |
| 1151T>A | V384D | 0.00 | Intolerant |
| 2101C>A | Q701K | 0.76 | Tolerated |
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